Colloidal Dispersion and Dispersion System of physical pharmaceutical 2nd.( semester-4) PHARMACY

 Colloidal Dispersion

Dispersion System:-

A Dispersion system is defined as a system in which dispersed phase is distributed uniformly through out dispersion medium.

 Classification of Dispersion system

S.N.            Dispersion medium           Dispersed phase           Example
1.                Gas                                      Liquid                            fog
2.                Gas                                      Solid                              Smoke
3.                Liquid                                  Gas                                Foam(aerosol)
4.                Liquid                                  Liquid                           Colloidal gold in water
5.                Liquid                                  Solid                             Oil globules or water globules
6.                Solid                                    Gas                                Solid foam
7.                Solid                                    Liquid                           Mineral oil in wax
8.                Solid                                    Solid                             Colloidal gold in glass

Colloidal Dispersion :-

A Dispersion system in which dispersed phase size range 1nm - 1um is distributed uniformly through out the dispersion medium are called as colloidal dispersion.

 Classification of colloidal dispersion  

Colloidal dispersion are classified into following types-
1. Lyophilic Colloidal 
2. Lyophobic Colloidal 
3. Association Colloidal

1. Lyophilic Colloidal :-  
  • Lyo means solvent .
  • Lyophilic colloidal are solvent loving colloidal.
  • They are hydrophilic and lipophilic types-
Hydrophilic  Colloidal include gelatin or acacia which form colloidal dispersion in water.
Lipophilic colloidal include rubber or polystyrene which forms colloidal dispersion in organic solvent.
eg.:- benzene
They are thermodynamically stable. Viscosity increase with adding dispersed phase.

2. Lyophobic colloidal:-

  • They are  knowns as solvent hating colloids.
  • When dispersion medium is water they are knowns hydrophobic colloids.
  • eg.:- Colloidal dispersion of gold or silver in water.
  • they are thermodynamically unstable.
  • Viscosity does not increase an adding dispersed phase.

3. Association Colloids :-

  • They are also knowns as amphilic colloids.
  • Few molecules or ions have both polar and non-polar groups.
  • They exists separately and associate at critical micelle concentration to form micelle of colloidal size.
  • Viscosity increase by adding amphiphiles.. 


 

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